Table 2 Expectations, benefits, and user-reported advantages of an injectable morphine compared to an oral formulation
From: People who inject oral morphine favor experimentation with injectable opioid substitution
Frequency (Number) | Percent | |
|---|---|---|
Would the availability of injectable morphine, for example in the form of vials of different dosages, be an alternative that you would accept? | ||
Yes | 132 | 95.0 |
No | 7 | 5.0 |
(Frequency missing = 18) | ||
Would the weekly pharmacy delivery of morphine vials for home self-injection be acceptable in your opinion? | ||
Yes | 129 | 92.8 |
No | 10 | 7.2 |
(Frequency missing = 18) | ||
In your opinion, what would be the benefit of making injectable morphine available? (You may check multiple answers) | ||
It would allow me to inject a cleaner product, in order to limit the risks of complications | 123 | 77.9 |
I would no longer need to buy morphine and/or heroin on illegal markets | 98 | 62.0 |
I could receive an injectable substitution covered by the National Health Insurance | 84 | 53.2 |
I could formalize a behavior that I already practice | 78 | 49.4 |
It would make available an injectable substitution in case of intolerance to oral substitution medication | 58 | 36.7 |
It would allow me to benefit from a transitory injectable substitution before switching to an oral treatment | 38 | 24.1 |
Other (specify) | 12 | 7.6 |
Could you tell us in a few words the advantages you expect from an injectable form compared to the capsules or tablets currently used? It would: | ||
Reduce the risks associated with the excipients of the oral galenic | 58 | 47.5 |
Reduce the risk of infection (hygiene, sterile product without contamination) | 52 | 42.6 |
Simplify preparation and reduce handling through using a galenic adapted to injection | 45 | 36.9 |
Improve knowledge, adaptability and reproducibility of the injected dose | 20 | 16.4 |
Guarantee the pharmaceutical quality of the injected substance | 18 | 14.8 |
Allow entering a validated care system, moving away from illicit markets, stopping the misuse of oral morphine | 6 | 4.9 |
Provide an alternative in case of insufficient efficiency of oral OST | 5 | 4.1 |
Obtain a more rapid psychoactive effect (maintenance of a shoot effect) | 4 | 3.3 |
Reduce the injection of other substances by better reducing the craving to inject | 3 | 2.5 |
Reduce stigma, recognize and manage injection as a behavioral addiction | 2 | 1.6 |
Reduce the financial cost by having injections covered by the National Health Insurance | 2 | 1.6 |