Characteristics | m (SD) or % | Unadj. p value | Adj. p value | ||
---|---|---|---|---|---|
All | FTS use | No FTS use | |||
N = 341 | N = 274 | N = 67 | |||
Site | Â | Â | Â | 0.016 | Â |
 Beloit | 71 (20.8) | 52 (19.0) | 19 (28.4) |  | 0.798 |
 Kenosha | 80 (23.5) | 58 (21.2) | 22 (32.8) |  | 0.009 |
 Madison | 79 (23.2) | 66 (24.1) | 13 (19.4) |  | 0.844 |
 Milwaukee | 111 (32.6) | 98 (35.8) | 13 (19.4) |  | Ref |
Age | 35.7 (8.6) | 35.4 (8.1) | 36.9 (10.3) | 0.600 | 0.807 |
Gender | Â | Â | Â | 0.677 | Â |
 Man | 202 (59.6) | 159 (58.5) | 43 (64.2) |  | Ref |
 Nonbinary | 7 (2.1) | 6 (2.2) | 1 (1.5) |  | 0.987 |
 Trans | 0 (0.0) | 0 (0.0) | 0 (0.0) |  |  |
 Women | 130 (38.3) | 107 (39.3) | 23 (34.3) |  | 0.988 |
Race and ethnicity | Â | Â | Â | 0.009 | Â |
 Black or African American, non-Hispanic | 24 (7.1) | 13 (4.8) | 11 (16.4) |  | 0.006 |
 Hispanic, any race | 21 (6.2) | 18 (6.6) | 3 (4.5) |  | 0.852 |
 Other or multiple categories, non-Hispanic | 32 (9.4) | 25 (9.2) | 7 (10.4) |  | 0.202 |
 White, non-Hispanic | 263 (77.4) | 217 (79.5) | 46 (68.7) |  | Ref |
Education | Â | Â | Â | 0.149 | Â |
 Less than high school degree | 38 (11.2) | 30 (11.0) | 8 (11.9) |  | 0.891 |
 High school, GED or equivalent | 162 (47.6) | 124 (45.4) | 38 (56.7) |  | Ref |
 Some college, trade school or 2y college | 129 (37.9) | 111 (40.7) | 18 (26.9) |  | 0.103 |
 4 years college degree or beyond | 11 (3.2) | 8 (2.9) | 3 (4.5) |  | 0.298 |
Employment | Â | Â | Â | 0.669 | Â |
 Employed and not job-seeking | 41 (12.1) | 35 (12.8) | 6 (9.0) |  | 0.254 |
 Unemployed and not job-seeking | 56 (16.5) | 44 (16.1) | 12 (17.9) |  | 0.489 |
 Unemployed and job-seeking | 243 (71.5) | 194 (71.1) | 49 (73.1) |  | Ref |
County is majority urban | 318 (93.8) | 255 (93.4) | 63 (95.5) | 0.536 | 0.665 |
Years of drug use | 12.2 (8.2) | 11.9 (7.9) | 13.0 (9.4) | 0.494 | 0.621 |
Age at first regular drug use | 23.5 (7.2) | 23.4 (7.4) | 23.9 (6.8) | 0.381 | – |
Current drug of choice |  |  |  | < 0.001 |  |
 Heroin | 241 (70.7) | 202 (73.7) | 39 (58.2) |  | Ref |
 Fentanyl | 43 (12.6) | 36 (13.1) | 7 (10.4) |  | 0.428 |
 Opioid analgesics | 10 (2.9) | 2 (0.7) | 8 (11.9) |  | < 0.001 |
 Cocaine or Crack Cocaine | 32 (9.4) | 23 (8.4) | 9 (13.4) |  | 0.336 |
 Methamphetamine | 15 (4.4) | 11 (4.0) | 4 (6.0) |  | 0.354 |
 Synthetics | 0 (0.0) | 0 (0.0) | 0 (0.0) |  |  |
 Prescription anxiety drugs | 0 (0.0) | 0 (0.0) | 0 (0.0) |  |  |
 Prescription amphetamines | 0 (0.0) | 0 (0.0) | 0 (0.0) |  |  |
 Some other drug | 0 (0.0) | 0 (0.0) | 0 (0.0) |  |  |
How often do you try to get drugs with fentanyl? | Â | Â | Â | 0.009 | 0.009 |
 Every time you get drugs | 17 (5.0) | 17 (6.2) | 0 |  |  |
 Most of the time | 49 (14.4) | 39 (14.3) | 10 (14.9) |  |  |
 Sometimes | 102 (30.0) | 86 (31.5) | 16 (23.9) |  |  |
 Rarely | 71 (20.9) | 60 (22.0) | 11 (16.4) |  |  |
 Never | 101 (29.7) | 71 (26.0) | 30 (44.8) |  |  |
Usual route of drug use |  |  |  | < 0.001 | - |
 Inject or shoot it into a vein | 299 (87.9) | 255 (93.4) | 44 (65.7) |  |  |
 Inject or shoot it into a muscle | 4 (1.2) | 2 (0.7) | 2 (3.0) |  |  |
 Snort it | 24 (7.1) | 10 (3.7) | 14 (20.9) |  |  |
 Smoke it | 12 (3.5) | 6 (2.2) | 6 (9.0) |  |  |
 Eat or swallow it | 1 (0.3) | 0 (0.0) | 1 (1.5) |  |  |
 Insert it rectally | 0 (0.0) | 0 (0.0) | 0 (0.0) |  |  |
 Use skin popping | 0 (0.0) | 0 (0.0) | 0 (0.0) |  |  |
 Some other method | 0 (0.0) | 0 (0.0) | 0 (0.0) |  |  |
Drug of choice use frequency in past 30Â days | Â | Â | Â | 0.103 | 0.650 |
 Less than once per day | 18 (5.3) | 12 (4.4) | 6 (9.0) |  |  |
 1 time per day | 15 (4.4) | 10 (3.6) | 5 (7.5) |  |  |
 2 times per day | 40 (11.7) | 30 (10.9) | 10 (14.9) |  |  |
 3 or more times per day | 268 (78.6) | 222 (81.0) | 46 (68.7) |  |  |
Polysubstance usea | 252 (73.9) | 210 (76.6) | 42 (62.7) | 0.020 | 0.764 |
Lifetime count of opioid overdose | 4.4 (8.4) | 4.7 (9.1) | 3.3 (4.5) | 0.202 | 0.517 |
Recent treatments used to stop or reduce useb | Â | Â | Â | Â | Â |
 Mutual help groups | 74 (21.8) | 60 (22.0) | 14 (20.9) | 0.847 | 0.973 |
 Group program like IOP | 73 (21.5) | 58 (21.2) | 15 (22.4) | 0.838 | 0.702 |
 Individual counseling | 154 (45.3) | 121 (44.3) | 33 (49.3) | 0.467 | 0.320 |
 Medications | 190 (55.9) | 156 (57.1) | 34 (50.7) | 0.345 | 0.669 |
 No treatment | 81 (23.8) | 66 (24.2) | 15 (22.4) | 0.758 | – |
 Other | 12 (3.5) | 11 (4.0) | 1 (1.5) | 0.313 | – |
Recent medications to stop or reduce useb,c |  |  |  |  | – |
 Buprenorphine formulations | 122 (64.6) | 100 (64.1) | 22 (66.7) | 0.780 |  |
 Extended-release naltrexone | 14 (7.4) | 13 (8.3) | 1 (3.0) | 0.291 |  |
 Methadone | 84 (44.4) | 75 (48.1) | 9 (27.3) | 0.029 |  |
 Other | 10 (5.3) | 7 (4.5) | 3 (9.1) | 0.283 |  |