Table 2 Odds of invasive bacterial infection in ALIVE participants with cessation and reduced intensity injection

Age (per 10 year)

1.18 (0.95–1.46)

0.135

1.30 (1.03–1.66)

0.029

1.21 (1.04–1.42)

0.012

1.34 (1.13–1.59)

0.001

Gender (female)

1.26 (0.86–1.84)

0.229

1.74 (1.17–2.57)

0.043

1.50 (1.14–1.97)

0.003

1.76 (1.34–2.32)

< 0.001

 HIV negative > 500 cells/mm³

1.0 (Ref)

3.13 (1.72–5.70)

<0.001

1.0 (Ref)

3.71 (2.03–6.79)

< 0.001

1.0 (Ref)

3.01 (1.97-4.59)

< 0.001

1.0 (Ref)

3.52 (2.3–5.39)

< 0.001

 200–499 cells/mm³

5.13 (3.21–8.19)

< 0.001

5.81 (3.63–9.29)

< 0.001

4.96 (3.57–6.88)

< 0.001

5.52 (3.97–7.69)

< 0.001

 < 200 cells/mm³

11.06 (6.98–17.55)

< 0.001

11.55 (7.23–18.43)

< 0.001

10.31 (7.41–14.3)

< 0.001

10.39 (7.44–14.5)

< 0.001

 High intensity

1.0 (Ref)

1.0 (Ref)

1.0 (Ref)

1.0 (Ref)

 Reduced intensity

0.74 (0.50–1.09)

0.126

0.64 (0.43–0.96)

0.031

0.81 (0.62–1.06)

0.121

0.74 (0.56–0.98)

0.035

 Cessation of injection

0.62 (0.36–1.07)

0.084

0.46 (0.25–0.84)

0.012

0.65 (0.45–0.95)

0.025

0.54 (0.36–0.81)

0.003