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Table 1 Characteristics of baseline BZD users and non-users

From: The impact of benzodiazepine use in patients enrolled in opioid agonist therapy in Northern and rural Ontario

 

Initially negative (n = 3288, 85.4%)

Initially positive (n = 562, 14.6%)

Male/female

1975 (60.1%)/1313 (39.9%)

316 (56.2%)/246 (43.8%)

North/South

1239 (37.7%)/2048 (62.3%)

166 (29.5%)/396 (70.5%)

Urban/rural

2753 (83.8%)/543 (16.2%)

499 (88.8%)/63 (11.2%)

Median age (Q 1, Q 3; SD)

30.8 (25.3, 39.4; SD = 10.2)

34.3 (28.1, 45.3; SD = 10.9)

Median peak methadone dose (Q 1, Q 3; SD)

75 (50, 100; SD = 33)

85 (55, 115; SD = 36)

Median peak suboxone dose ( Q 1, Q 3; SD)

8 (8, 16; SD = 7)

12 (8, 20; SD = 8)

Median days retained (Q 1, Q 3; SD)

265 (56, 526; SD = 272)

215 (53, 519; SD = 270)

Median percent positive results (Q 1, Q 3; SD)

0.0 (0.0, 0.0; SD = 4.9)

21.4 (6.8, 55.1; SD = 32.1)

Percent positive results

[0, 25)

3252 (98.9%)

302 (53.7%)

[25, 50)

31 (0.9%)

96 (17.1%)

[50, 75)

4 (0.1%)

68 (12.1%)

[75, 100]

1 (<0.1%)

96 (17.1%)

At month 3

Day 60 to 90

Positive/negative

144 (6.0%)/2276 (94.0%)

204 (50.5%)/200 (49.5%)

Retained

2420 (73.6%)

404 (71.9%)

At Month 6

Day 150 to 180

Positive/negative

109 (5.6%)/1850 (94.4%)

128 (40.9%)/185 (59.1%)

Retained

1959 (59.6%)

313 (55.7%)

At Month 9

Day 240 to 270

Positive/negative

88 (5.2%)/1601 (94.8%)

104 (39.0%)/163 (61.0%)

Retained

1689 (51.4%)

267 (47.5%)

At Month 12

Day 330 to 360

Positive/negative

80 (5.3%)/1443 (94.7%)

74 (31.2%)/163 (68.8%)

Retained

1523 (46.3%)

237 (42.2%)

Retained/not retained 365 Days

1447 (44.0%)/1841 (56.0%)

224 (39.9%)/338 (60.1%)

  1. Descriptive statistics were summarized for baseline characteristics of patients, and standardized differences were used to compare patient groups. Patients were considered baseline BZD users if they had any BZD positive urine samples in the first month of treatment