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Table 1 Factors associated with non-medical use of opioids during opioid maintenance treatment: univariate analyses.

From: Non-medical use of opioids among HIV-infected opioid dependent individuals on opioid maintenance treatment: the need for a more comprehensive approach

 

Number of visits

(%) or median [IQR]

Nb. of patients

Coefficient

(95% CI)

p-value

Buprenorphine (ref)

640 (60.6)

154

  

Methadone

416 (39.4)

111

0.00 (-0.41; 0.37)

0.98

Female gender

286 (27.1)

72

0.16 (-0.09; 0.39)

0.20

Agea

36 [32-39]

 

-0.69 (-0.96; -0.43)

< 10 -3

Owner or renter of their house

757 (71.7)

189

-0.24 (-0.45; 0.00)

0.03

Good housing conditionsb

868 (82.4)

210

-0.13 (-0.39; 0.08)

0.22

Heavy drinkingc

213 (20.4)

95

0.15 (-0.07; 0.40)

0.20

Cocaine used

277 (26.3)

115

0.91 (0.67; 1.20)

< 10 -3

Cannabis use (daily)d

467 (44.4)

156

0.45 (0.29; 0.62)

< 10 -3

Benzodiazepine consumptiond

358 (33.9)

150

0.62 (0.44; 0.81)

< 10 -3

HIV clinical stage

    

A (ref)

474 (44.9)

138

  

B

518 (49.1)

125

-0.24 (-0.49; -0.01)

0.06

C

63 (6.0)

22

-0.68 (-1.17; -0.28)

0.003

Depressive symptomse

666 (63.2)

200

0.34 (0.18; 0.52)

< 10 -3

Withdrawal symptoms

204 (19.3)

122

0.81 (0.56; 1.07)

< 10 -3

Time since first injection (years)a

16 [13-20]

 

-0.56 (-0.86; -0.32)

< 10 -3

Time since first positive HIV test (years)a

11 [8-13]

 

-1.00 (-1.35; -0.76)

< 10 -3

Time since OMT initiation (months)f

16 [7-30]

 

-0.29 (-0.39; -0.22)

< 10 -3

Undetectable viral charge

366 (34.9)

124

-0.25 (-0.46; -0.03)

0.03

CD4 cell count/mm3 < 200

57 (5.5)

32

-0.26 (-0.65; 0.15)

0.20

Receiving ART

395 (37.4)

119

-0.52 (-0.70; -0.30)

< 10 -3

Complete trust in physicians

824 (78.4)

196

-0.33 (-0.62; 0.10)

0.01

Low prescribed dose of OMTg

676 (66.8)

169

-0.22 (-0.43;0.04)

0.06

  1. *MANIF 2000 cohort, N = 235, 1056 visits.
  2. a For ten years increase.
  3. b Good housing conditions were defined as the rank 3 and 4 (quite or very comfortable vs. uncomfortable or low comfort) using a four-point Likert scale.
  4. c Heavy drinking was defined as drinking more than 4 alcohol units on any one occasion.
  5. d During the previous 6 months.
  6. e Patients were defined with depressive symptoms if CES-D > 17 for men and > 23 for women.
  7. f For one year increase.
  8. gPrescribed dose of OMT is low if the methadone dose was less than 60 mg per day or the buprenorphine dose was less than 8 mg per day.